항암식물-안개꽃

                          안개꽃(Gypsophila Paniculata)에 강력(强力) 항암성분(抗癌成分)

                                                              

안개꽃 : 'Baby's Breath' 석죽과 한해살이 식물인 안개꽃 (학명: gypsophila paniculata)에 백혈병 치료에 혁명을 불러올 수 있는 강력한 항암물질이 들어있다는 연구결과가 나왔다고 영국의 BBC인터넷판 등이 2010년 4월 29일 보도했다. 영국 사우샘프턴 종합병원 백혈병연구소는 안개꽃에 들어있는 사포닌(saponin)이라는 분자가 백혈병세포에 흡수된 뒤 암세포 막에 구멍을 뚫어 항암제가 들어가기 쉽게 만들어 항암제의 효능을 "100만배 이상" 증폭시킨다고 밝혔다. 따라서 독소가 첨가된 항체를 이 분자와 함께 투여하면 백혈병세포를 뚫고 들어가 훨씬 빨리 암세포를 죽일 수 있다고 연구팀을 이끈 데이비드 플라벨 (David Flavell) 박사는 밝혔다.

첫 실험에서는 이 항체가 주입된 지 몇 시간 안에 백혈병세포의 99.9%가 죽은 것으로 나타났다.

연구팀은 이 결과에 너무 놀라 실험장비가 손상된 것으로 의심했으나 수십 번 실험을 반복해도 똑같은

결과가 나왔다고 플라벨 박사는 밝혔다.
그는 이 새로운 치료법이 백혈병만이 아니라 많은 다른 종류의 암에도 효과가 있을 가능성이 크다고 말했다.
이 실험결과는 임상시험을 통해 확인하려면 앞으로 3-5년이 걸릴 것이라고 그는 덧붙였다.

플라벨 박사는 20년 전 아들 사이먼이 백혈병으로 죽자 백혈병연구협회(Leukemia Busters)를 만들어

백혈병 치료법을 연구해 오다가 사우샘프턴 종합병원에 백혈병연구소를 차렸다.

이 연구결과는 지난주 미국 워싱턴에서 열린 미국암연구학회(American Association for Cancer Research)

연례회의에서 발표되었다.

[연합뉴스][중앙일보] 2010.4.30. 

 

[아침안개 추가자료]

▲ Dr David Flavell과 부인 Dr Bee Flavell

Dr David Flavell. 56세  University of Southampton [사우샘프턴 종합병원]교수. School: Medicine (Simon Flavell Leukaemia Reseach Laboratory) Faculty: Medicine, Health and Life Sciences Telephone Number: 023 8079 6947 023 8079 6528 E-mail: d.j.flavell@soton.ac.uk   Subject : Leukaemia Children's leukaemia research Monoclonal antibodies for leukaemia diagnosis and therapy

[영국의 미러(Mirror)紙 보도기사 원문]

Doctor parents in cancer drug boost

By Euan Stretch. 29/04/2010

 

A couple who lost their only son to leukaemia unveiled a medical breakthrough yesterday that could save the lives

of thousands of cancer patients.

 

Doctors David and Bee Flavell, both research scientists, have discovered that an extract from the white flower

commonly known as 'Baby's Breath' can boost the efficiency of anti-cancer drugs by a staggering nine million

times.

 

They found that molecules called saponins, extracted from the 'Gypsophila Paniculata' plant, appear to break

down the membrane of cancer cells.

 

This makes it much easier for antibody-based drugs, known as immunotoxins, to attack the cancerous cells.

 

The groundbreaking discovery was made by the couple and three other researchers working for the charity

Leukaemia Busters, set up by the Flavells after son Simon died of an incurable form of the cancer in 1990,

aged 10.

 

Scientists carried out the work at the newly refurbished Simon Flavell Leukaemia Research Laboratory at

Southampton General Hospital.

 

Dr David Flavell, 56, said:

"I am usually careful about the words I use with things like this but this discovery could truly revolutionise the way

these antibody-based drugs work and it will save lives.

"We've been working towards this since Simon's death."

 

Last week, the Flavells presented their findings at a conference in Washington, organised by the

American Association for Cancer Research.

[원본기사. www.mirror.co.uk]

 

 

[ Mail online 기사]

Baby's Breath flower can boost anti-leukaemia drugs by up to a million times

By Daily Mail Reporter (Last updated at 6:49 AM on 29th April 2010)

Scientists unveiled a major medical breakthrough that could revolutionise the treatment of leukaemia patients and

save thousands of lives.

 

Experts have discovered that an extract from the white flower commonly known as Baby's Breath can boost

the efficiency of anti-cancer drugs by a staggering million times.

 

They found that molecules called saponins, extracted from the Gypsophila Paniculata plant,

appear to break down the membrane of cancer cells.

 

This makes it much easier for antibody-based drugs, known as immunotoxins, to attack the cancerous cells.

 

As a result, immunotherapy used to treat certain types of leukaemia and lymphoma is increased in potency

by 'over one million-fold'.

 

The groundbreaking discovery has been made by scientists working for the charity Leukaemia Busters,

based in Southampton, Hampshire.

The charity is run by David and Bee Flavell, who son Simon died with an incurable form of childhood leukaemia in 1990, aged ten.   Scientists carried out the work at the newly refurbished Simon Flavell Leukaemia Research Laboratory at Southampton General Hospital.   Dr David Flavell said: 'I am usually careful about the words I use with things like this but this discovery could truly revolutionise the way these antibody-based drugs work and it will save lives.   'And this doesn't just apply to leukaemia, there is a really big possibility this can be used for many cancers too.   'This is a potentially very important discovery that could allow us to kill leukaemia cells in the patient much more effectively with much lower doses of immunotoxin 'The challenge now is to establish how best to apply this laboratory discovery to the treatment of patients.

'We are all excited at the major advance this could represent for immunotoxin treatments for leukaemia.'

 

The next step is to take the findings from the test tube and into clinical trials to turn it into a treatment that can be

made available to patients.

 

If that is successful - a process that could take between three to five years - then thousands of leukaemia patients

could benefit from lower doses of drugs.

 

The breakthrough has come as a result of 12 months of research and testing in collaboration with scientists

based in the Berlin.

 

Dr Flavell added: 'We still need to do laboratory-based work to further develop this discovery into a practical and

safe treatment for patients and money is the key to achieving this.

 

'Leukaemia Busters scientists and doctors have worked tirelessly day and night over many years and have

relied on the generosity of donations to fund a great deal of their work.'

 

The name Leukaemia Busters and its logo were both devised by Simon Flavell before he died.

The youngster was a great fan of Ghost Busters[

[Mail online] Associated Newspapers Ltd 2010.4.29. <원문보기>

 

출  처 : http://citrain64.blog.me/100104534582

 

 

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